Current Issue : January - March Volume : 2015 Issue Number : 1 Articles : 4 Articles
The desire to maintain a youthful appearance in an aging population has accelerated\nseveral advancements in the cosmeceuticals market. The term cosmeceutical defines products\ncontaining bioactive substances that cannot be considered cosmetics or drugs. A variety of\ningredients have been used in cosmeceuticals to improve the health and appearance of aged skin,\nand during the past decade, the utility of botanical natural products have gained much attention in the\nWest. Throughout this review, the skin aging, and photoaging are discussed, mechanisms which\nunderlie these processes are explored, and treatment options using natural plant extracts are\nexamined....
Among marine organisms, marine algae are rich sources of structurally diverse bioactive compounds with various\nbiological activities. Algae are widespread everywhere on earth where there is light to carry out photosynthesis and\nhave the potential to produce a number of valuable compounds like Polyunsaturated Fatty Acids (PUFAs), pigments,\nand antioxidants for pharmaceuticals, biomedical and nutraceutical products. This review considers recent progress in\nthe application of bioactive substances derived from marine algae as potential cosmeceuticals. The biological activities\nof terpenoids, carotenoids, tocopherol, phenolic compounds, polysaccharides (fucoidan, carrageenans, alginates and\nagar), unsaturated fatty acids and mycosporin-like amino acids are reported in order to evaluate their potential use in\nfuture cosmetic skin care products....
Chloasma, or melasma, is a commonly acquired pigmentary disorder among Asian women. It may be considered as a\nphysiological change during pregnancy. The incidence in Asian women is higher than that in other ethnic groups but\nfurther epidemiologic data are needed. There are very few studies related to the benefits of sunscreens to prevent this\ndermatosis. The aim of this study was to assess the effectiveness of a broad-spectrum sunscreen in the prevention of\nmelasma in Korean pregnant women. We tested the effectiveness and tolerance of a sunscreen product (SPF 50+,\nUVA-PF 30) during a 12-month clinical trial including 220 Korean parturients with skin type III and IV. 217 women\ncompleted the study. Only 3 (1%) of the study population developed melasma, which was mild (MASI grade between\n1.2 and 2.7). In addition, the clinical effectiveness of the evaluated sunscreen was judged ââ?¬Å?good to excellentââ?¬Â by the\nmajority of study participants and by the research dermatologists. The ââ?¬Å?excellentââ?¬Â tolerance of the sunscreen under\nevaluation was confirmed ââ?¬Å?goodââ?¬Â to ââ?¬Å?excellentââ?¬Â in 95% and 97% of cases. This study clearly demonstrates that this\nbroad-spectrum sunscreen is well tolerated and effective in the prevention of melasma in Korean pregnant women. Although\ntreatment remains elusive, prevention is possible....
The aim of this study was to evaluate the influence of the depth of the dermis\non the measured collagen and elastin levels and to establish the correlation between\nthe amount of these two extra cellular matrix (ECM) components and age. Multiphoton\nMicroscopy (MPM) that measures the auto fluorescence (AF) and second harmonic\ngeneration (SHG) was used to quantify the levels of elastin and collagen and to determine\nthe SAAID (SHG-to-AF Aging Index of Dermis) at two different skin depths. A 50 MHz\nultrasound scanner was used for the calculation of the Sub Epidermal Non Echogenic Band\n(SENEB). The measurements of the skin mechanical properties were done with a cutometer.\nAll measurements were performed on two groups of 30 healthy female volunteers.\nThe MPM showed a decrease of the quantity of collagen and elastin as a function of depth\nof the dermis as well as age. The SAAID was lower for the older skin in the deeper dermis.\nUltrasound imaging revealed a significant decrease of SENEB as a function of aging.\nThe mechanical properties confirmed a loss of cutaneous elasticity and firmness. Although\nmultiphoton microscopy is a powerful technique to study the characteristics of the dermis\nand its age-related damage, the location of the measurements (depth) remains very\nimportant for the validation of these variations. These variations do not seem to be\nhomogeneous according to the part of the dermis that is studied....
Loading....